Ataxia - Kyle Bryant Translational Research Award 2018

Friedreich's Ataxia Research Alliance (FARA) invites proposals for its annual Kyle Bryant Translational Research Award. Deadline for submission of Letters of Intent is May 15, 2018. Proposals must focus on pre-clinical and clinical investigations that will advance treatments for Friedreich's Ataxia (FA). The applicant may request a budget of up to $ 250,000 per year for one or two years.

The specific aims must target one or more of the following:

• Identification of biomarkers for FA that will elucidate disease variability, severity, and prognosis; facilitate drug screening, and/or optimise selection of patients and clinical endpoints for clinical trials;
• Development of tools and technologies that can:
• be directly used for therapy development,
• overcome existing obstacles to treatment and
• be directly applied to, or adapted for, delivery of potential therapeutics;
• Pre-clinical development and testing of potential therapeutics, biologics, and devices in cells and animals;
• Clinical studies of patient outcome measures, potential interventions, or devices.